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Engineered particles of purified sand may very well be a possible remedy for weight problems


Engineered pure sand particles may very well be the subsequent anti-obesity remedy as new analysis from the College of South Australia reveals that porous silica can forestall fat and carbohydrates from being absorbed within the physique.

The engineered silica beads are constructed from pure sand and are optimally engineered with a excessive floor space that enables them to soak up massive quantities of digestive enzymes, fat and sugars within the digestive tract.

Funded by the Channel 7 Youngsters’s Analysis Basis, this research is the primary to validate how porous silica particles can intrude with digestion and block the absorption of fat and sugars.

Developed in partnership with Glantreo Restricted, the brand new silica-based remedy will likely be gentler on the abdomen with fewer disagreeable negative effects related to the mainstream anti-obesity drug, Orlistat.

Lead researcher Dr Paul Joyce of UniSA mentioned this groundbreaking discovering might change the well being outcomes of billions of individuals battling weight problems.

Weight problems is a world drawback that impacts greater than 1.9 billion individuals worldwide.

Regardless of this, there may be at the moment an absence of efficient therapies with out the negative effects – similar to diarrhea, bloating and stomach ache – that always preserve individuals from beginning remedy.

Styrofoam silica is receiving rising consideration for its anti-obesity potential, with human trials exhibiting it to be a protected remedy. Nevertheless, precisely the way it works has been elusive by researchers – till now.

Our research reveals how porous silica promotes anti-obesity results by performing domestically within the intestine to restrict the digestion and absorption of fat and carbohydrates.

Importantly, the mild mechanism is anticipated to offer clinically efficient weight reduction outcomes with no negative effects. “

Dr. Paul Joyce, Principal Investigator, UniSA

Weight problems is a threat issue for a lot of persistent illnesses and situations similar to heart problems, sort II diabetes, and most cancers, and is related to larger mortality. In Australia, two-thirds of adults and one-quarter of youngsters are thought of obese or overweight.

The test-tube research examined a number of silica samples underneath situations that mimic the digestive setting through the digestion of a high-fat, high-carbohydrate meal.

It discovered that porous silica particles with a pore width of 6–10 nm had been best for triggering an inhibitory response to each fat and sugars.

Dr Joyce mentioned: “This research recognized particular parameters for porous silica to have anti-obesity results.

“The following steps are to substantiate these findings with animal fashions of weight problems in order that we will determine any variants for optimum anti-obesity situations.

“Weight problems is a very preventable illness. This is a vital step ahead in tackling probably the most preventable well being situations on this planet.”


College of South Australia

Reference journal:

Chen, JY et al. (2022) Anti-obesity impact of porous silica will depend on pore nanostructure, particle dimension and floor chemistry in an in vitro digestion mannequin. Medication.


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